Search Result
Results for "
cationic lipids
" in MedChemExpress (MCE) Product Catalog:
55
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-112754A
-
|
1,2-Dioleoyl-3-trimethylammonium-propane chloride
|
Liposome
|
Cancer
|
|
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
|
-
-
- HY-153379
-
|
|
Liposome
|
Others
|
|
ALC-0315 analogue-1 (compound P-10) is a cationic lipid. ALC-0315 analogue-1 is the raw material for synthesis of cationic liposome .
|
-
-
- HY-142999
-
-
-
- HY-160553
-
|
|
Liposome
|
Others
|
9322-O16B, an ionizable cationic lipid, is used for LNP generation .
|
-
-
- HY-W800776
-
|
1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide
|
Liposome
|
Others
|
|
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
|
-
-
- HY-139305
-
|
|
Liposome
|
Cancer
|
|
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
|
-
-
- HY-154804
-
|
|
Liposome
|
Others
|
|
DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids .
|
-
-
- HY-129990
-
|
|
Liposome
|
Cancer
|
|
Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport .
|
-
-
- HY-125734
-
|
|
Liposome
|
Others
|
|
DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
|
-
-
- HY-144014
-
|
|
Liposome
|
Others
|
|
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA .
|
-
-
- HY-157252
-
|
|
Liposome
|
Cancer
|
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
-
- HY-143688
-
|
|
Liposome
|
Others
|
|
EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents .
|
-
-
- HY-143702
-
|
NBD-DOTAP
|
Liposome
|
Inflammation/Immunology
Cancer
|
|
Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery . Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm).
|
-
-
- HY-130751
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DODAP is a cationic lipid. The ionizable lipid DODAP is the lipid component of liposomes (pKa = 5.59 in TNS binding tests). DODAP can be used for siRNA encapsulation and in vitro and in vivo delivery of immunostimulated chemotherapeutic active molecules .
|
-
-
- HY-W409806
-
|
|
Others
|
Inflammation/Immunology
|
|
Cholesterylamine is a cationic lipid. Cholesterylamine can be added to the PLGA to prepare PLGA particle having surface charge. Cholesterylamine can be used for drug delivery. Cholesterylamine can be used for autoimmune diseases and allergy research .
|
-
-
- HY-160275
-
|
|
Liposome
|
Others
|
|
DOPE-PEG-Fluor 555,MW 2000 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
-
- HY-139200
-
|
|
Liposome
|
Others
|
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
-
- HY-W414069
-
|
|
Endogenous Metabolite
Liposome
|
Others
|
|
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
|
-
-
- HY-147087
-
|
|
Liposome
|
Cancer
|
|
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
|
-
-
- HY-112005
-
|
dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Liposome
Endogenous Metabolite
|
Inflammation/Immunology
|
|
DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
-
- HY-112755
-
|
|
Liposome
|
Others
|
|
DODMA, a cationic lipid, is used for the preparation of liposomes .
|
-
-
- HY-145739
-
-
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
Liposome
|
Others
|
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
-
- HY-144025
-
|
|
Liposome
|
Others
|
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
-
- HY-149156
-
|
|
Liposome
|
Cancer
|
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
-
- HY-W590532
-
|
|
Liposome
|
Others
|
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
-
- HY-W800783
-
|
CDESA
|
Liposome
|
Others
|
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
-
-
- HY-156985
-
|
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
|
-
-
- HY-W590549
-
|
DODAC
|
Others
|
Others
|
|
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .
|
-
-
- HY-153372
-
|
|
Liposome
|
Others
|
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
-
- HY-133952
-
|
|
Liposome
|
Cancer
|
|
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .
|
-
-
- HY-W590548
-
|
|
Liposome
|
Others
|
|
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
-
-
- HY-145225
-
|
|
Liposome
|
Others
|
|
DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid .
|
-
-
- HY-46760
-
|
|
Liposome
|
Others
|
|
CCD Lipid01 is a cationic lipid useful in the delivery of biologically active agents to cells and tissues (extracted from patent WO2015095340 A1) .
|
-
-
- HY-W590531
-
-
-
- HY-142996
-
|
|
Liposome
|
Cancer
|
|
BGTC is a non-amino acid cationic lipid. BGTC can be used for delivery of nucleic acids .
|
-
-
- HY-112523A
-
|
|
Others
|
Others
|
|
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs .
|
-
-
- HY-151511
-
|
|
Liposome
|
Cancer
|
|
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
|
-
-
- HY-142998
-
-
-
- HY-144021
-
|
|
Liposome
|
Others
|
|
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
|
-
-
- HY-W590678
-
|
|
Liposome
|
Others
|
|
SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
|
-
-
- HY-112251
-
D-Lin-MC3-DMA
Maximum Cited Publications
45 Publications Verification
|
Liposome
|
Cancer
|
|
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
|
-
-
- HY-144022
-
-
-
- HY-148830
-
|
|
Liposome
|
Others
|
|
Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
|
-
-
- HY-144023
-
|
|
Liposome
|
Others
|
|
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
|
-
-
- HY-143210
-
|
|
Liposome
|
Metabolic Disease
|
|
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
|
-
-
- HY-153125
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DLRIE can be used for the synthesis of cationic lipid GAP-DLRIE which can be used to enhance the delivery and expression of plasmid DNA .
|
-
-
- HY-156448
-
|
|
Liposome
|
Cancer
|
|
80-O14B is an cationic lipid-like compound for CRISPR/Cas9 delivery .
|
-
-
- HY-156936
-
|
|
Liposome
|
Others
|
|
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
-
- HY-134541
-
|
|
Liposome
|
Infection
|
|
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
|
-
- HY-153737
-
|
|
Liposome
|
Others
|
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-W598178
-
|
|
Liposome
|
Others
|
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
-
- HY-144020
-
|
|
Liposome
|
Others
|
|
14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery .
|
-
- HY-154803
-
|
DLin-M-C2-DMA
|
Others
|
Others
|
|
DLin-M-K-DMA (DLin-M-C2-DMA) is a cationic lipid that can be used in the construction of biological delivery vectors .
|
-
- HY-156616
-
|
|
Liposome
|
Inflammation/Immunology
|
|
VC1052 is the component of HY-142998 Vaxfectin. Vaxfectin is a cationic lipid-based adjuvant that can be used for plasmid DNA- and protein-based vaccines .
|
-
- HY-112763
-
|
|
Liposome
|
Inflammation/Immunology
|
|
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
|
-
- HY-149037
-
|
N4-Spermine cholesteryl carbamate
|
Liposome
|
Others
|
|
GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-149037A
-
|
N4-Spermine cholesteryl carbamate pentahydrochloride
|
Liposome
|
Others
|
|
GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-142654
-
|
|
Liposome
|
Others
|
|
ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
|
-
- HY-W440683
-
|
|
Liposome
|
Others
|
|
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440681
-
|
|
Liposome
|
Others
|
|
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440684
-
|
|
Liposome
|
Others
|
|
C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440682
-
|
|
Liposome
|
Others
|
|
C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-145405
-
C12-200
5 Publications Verification
|
Liposome
|
Others
|
|
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .
|
-
- HY-W590681
-
|
|
Liposome
|
Others
|
|
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-W590679
-
|
|
Liposome
|
Others
|
|
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-160552
-
|
|
Liposome
|
Others
|
|
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
|
-
- HY-144016
-
|
|
Liposome
|
Others
|
|
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
|
-
- HY-112758
-
|
|
Liposome
|
Others
|
|
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
|
-
- HY-151512
-
-
- HY-112251S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
- HY-152229
-
|
|
Liposome
|
Cancer
|
|
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
|
-
- HY-142997
-
|
|
Liposome
|
Others
|
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
- HY-131119
-
|
Dioctadecyldimethylammonium bromide; DODAB
|
Liposome
|
Others
|
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
-
- HY-138170
-
|
|
Liposome
SARS-CoV
|
Infection
|
|
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-112754A
-
|
1,2-Dioleoyl-3-trimethylammonium-propane chloride
|
Drug Delivery
|
|
DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
|
-
- HY-154804
-
|
|
Drug Delivery
|
|
DLin-M-C4-DMA (Compound MC4) is a cationic lipid. DLin-M-C4-DMA can be used for delivery of nucleic acids .
|
-
- HY-144014
-
|
|
Drug Delivery
|
|
MVL5 is a non-degradable multivalent cationic lipid. MVL5 is a highly efficient vector for both DNA and siRNA .
|
-
- HY-153379
-
|
|
Drug Delivery
|
|
ALC-0315 analogue-1 (compound P-10) is a cationic lipid. ALC-0315 analogue-1 is the raw material for synthesis of cationic liposome .
|
-
- HY-142999
-
|
|
Drug Delivery
|
|
DOIC is a cationic lipid that can be used for RNA vaccines .
|
-
- HY-157252
-
|
|
Drug Delivery
|
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-143688
-
|
|
Drug Delivery
|
|
EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents .
|
-
- HY-143702
-
|
NBD-DOTAP
|
Drug Delivery
|
|
Fluorescent DOTAP, a cationic lipid, can be used for the research of nucleic acid and protein delivery . Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm).
|
-
- HY-130751
-
|
|
Drug Delivery
|
|
DODAP is a cationic lipid. The ionizable lipid DODAP is the lipid component of liposomes (pKa = 5.59 in TNS binding tests). DODAP can be used for siRNA encapsulation and in vitro and in vivo delivery of immunostimulated chemotherapeutic active molecules .
|
-
- HY-160275
-
|
|
Drug Delivery
|
|
DOPE-PEG-Fluor 555,MW 2000 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-139200
-
|
|
Drug Delivery
|
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
- HY-W414069
-
|
|
Drug Delivery
|
|
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
|
-
- HY-147087
-
|
|
Drug Delivery
|
|
YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo .
|
-
- HY-112005
-
|
dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Drug Delivery
|
|
DOPE (dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-112755
-
|
|
Drug Delivery
|
|
DODMA, a cationic lipid, is used for the preparation of liposomes .
|
-
- HY-145739
-
-
- HY-112757
-
DLinDMA
1 Publications Verification
|
Drug Delivery
|
|
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .
|
-
- HY-144025
-
|
|
Drug Delivery
|
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
- HY-149156
-
|
|
Drug Delivery
|
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
- HY-W590532
-
|
|
Drug Delivery
|
|
306-O12B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-153372
-
|
|
Drug Delivery
|
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
- HY-133952
-
|
|
Drug Delivery
|
|
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .
|
-
- HY-145225
-
|
|
Drug Delivery
|
|
DLin-K-C3-DMA, a cationic lipid, can be used in the synthesis of nucleic acid-lipid particle to delivery of nucleic acid .
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- HY-46760
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Drug Delivery
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CCD Lipid01 is a cationic lipid useful in the delivery of biologically active agents to cells and tissues (extracted from patent WO2015095340 A1) .
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- HY-142996
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Drug Delivery
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BGTC is a non-amino acid cationic lipid. BGTC can be used for delivery of nucleic acids .
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- HY-151511
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Drug Delivery
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A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle .
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- HY-142998
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Drug Delivery
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Vaxfectin is a cationic lipid-based adjuvant that can be used for plasmid DNA- and protein-based vaccines .
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- HY-144021
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Drug Delivery
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14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
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- HY-W590678
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Drug Delivery
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SSPalmO-Phe is an ionizable cationic self-degradable disulfide-cleavable (SS-cleavable) proton-activated lipid-like material. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for drug delivery.
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- HY-112251
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D-Lin-MC3-DMA
Maximum Cited Publications
45 Publications Verification
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Drug Delivery
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D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
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- HY-144022
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Drug Delivery
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16:0 DAP is a cationic lipids that can be used for drug delivery, gene transfection and vaccine delivery .
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- HY-148830
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Drug Delivery
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Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
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- HY-144023
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Drug Delivery
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16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
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- HY-143210
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Drug Delivery
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Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .
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- HY-156448
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Drug Delivery
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80-O14B is an cationic lipid-like compound for CRISPR/Cas9 delivery .
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- HY-134541
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Drug Delivery
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SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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- HY-153737
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Drug Delivery
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113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
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- HY-144020
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Drug Delivery
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14:0 DAP (1,2-dimyristoyl-3-dimethylammonium-propane ) is a cationic lipid that can be used for drug delivery .
|
-
- HY-156616
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|
|
Drug Delivery
|
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VC1052 is the component of HY-142998 Vaxfectin. Vaxfectin is a cationic lipid-based adjuvant that can be used for plasmid DNA- and protein-based vaccines .
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- HY-112763
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Drug Delivery
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CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
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- HY-149037
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N4-Spermine cholesteryl carbamate
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Drug Delivery
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GL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-149037A
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N4-Spermine cholesteryl carbamate pentahydrochloride
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Drug Delivery
|
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GL67 (N4-Spermine cholesteryl carbamate) (pentahydrochloride) is a cationic lipid. GL67 can be used for nucleic acid agents and vaccines delivery, and gene transfection .
|
-
- HY-142654
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|
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Drug Delivery
|
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ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively .
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-
- HY-W440683
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Drug Delivery
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C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440681
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Drug Delivery
|
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C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440684
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|
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Drug Delivery
|
|
C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440682
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|
|
Drug Delivery
|
|
C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-145405
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C12-200
5 Publications Verification
|
Drug Delivery
|
|
C12-200 is an ionizable cationic lipid and auxiliary lipid. C12-200 is commonly used for mRNA delivery. Administration of human erythropoietin (EPO) mRNA or factor VII siRNA increased and decreased serum factor VII levels, respectively, in LNPs mice containing C12-200 .
|
-
- HY-144016
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|
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Drug Delivery
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16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
|
-
- HY-112758
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|
|
Drug Delivery
|
|
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
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- HY-151512
-
|
|
Drug Delivery
|
|
A12-Iso5-4DC19 is an ionizable cationic lipid. A12-Iso5-4DC19 can facilitate mRNA delivery and be used for the research of RNA vaccines .
|
- HY-152229
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Drug Delivery
|
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G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
|
- HY-142997
-
|
|
Drug Delivery
|
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DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
- HY-131119
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Dioctadecyldimethylammonium bromide; DODAB
|
Drug Delivery
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Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
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- HY-138170
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Drug Delivery
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ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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- HY-K2016
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MCE Protein Transfection Reagent is a cationic lipid mixture for complexation with proteins, peptides, antibodies and other biologically active molecules to allow their direct intracellular delivery.
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-112251S
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D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
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